miR-193b-5p and miR-374b-5p Are Aberrantly Expressed in Endometriosis and Suppress Endometrial Cell Migration In Vitro
Frisendahl C, Tang Y, Boggavarapu NR, Peters M, Lalitkumar PC, Piltonen TT, Arffman RK, Salumets A, Goette M, Korsching E, Gemzell-Danielsson K
Biomolecules. 14(11), 1400. doi: 10.3390/biom14111400, 2024
Interplay of miR-542, miR-126, miR-143 and miR-26b with PI3K-Akt is a Diagnostic Signal and Putative Regulatory Target in HPV-Positive Cervical Cancer
Rahimi-Moghaddam A, Ghorbanmehr N, Gharbi S, Nili F, Korsching E
Biochem Genet. 2024 Jun 7. doi: 10.1007/s10528-024-10837-y, 2024
Bromocriptine inhibits proliferation in the endometrium from women with adenomyosis
Tang Y, Ponandai-Srinivasan S, Frisendahl C, Andersson JK, Pavone D, Stewart EA, Lalitkumar PGL, Korsching E, Bogavarappu NR, Gemzell-Danielsson K
Front Endocrinol (Lausanne). 14:1026168. doi: 10.3389/fendo.2023.1026168, 2023
Digital Holographic Microscopy for Label-Free Detection of Leukocyte Alternations Associated with Perioperative Inflammation after Cardiac Surgery
Steike DR, Hessler M, Korsching E, Lehmann F, Schmidt C, Ertmer C, Schnekenburger J, Eich HT, Kemper B, Greve B
Cells. 11(4):755. doi: 10.3390/cells11040755, 2022
Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells
Korsching E, Matschke J, Hotfilder M
International Journal of Molecular Medicine. 49, 3: 39. doi: 10.3892/ijmm.2022.5094, 2022
Characterization of the first microRNA in human CDH1 that affects cell cycle and apoptosis and indicates breast cancers progression
Gharbi S, Mohammadi Z, Saedi Dezaki M, Dokanehiifard S, Dabiri S, Korsching E
J Cell Biochem. 1-16. doi: 10.1002/jcb.30211, 2022
Statins: Complex outcomes but increasingly helpful treatment options for patients
Mohammadkhani N, Gharbi S, Fatima H, Farzaneh A, Mahjoob G, Hoseinsalari A, Korsching E
Eur J Pharmacol. 863:172704. doi: 10.1016/j.ejphar.2019.172704, 2019
Defining a Characteristic Gene Expression Set Responsible for Cancer Stem Cell Like Features in a sub-population of Ewing Sarcoma Cells
Hotfilder M, Mallela N, Seggewiß J, Dirksen U, Korsching E
Int. J. Mol. Sci. 19:3908; doi: 10.3390/ijms19123908, 2018
miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer
Ghorbanmehr N, Gharbi S, Korsching E, Tavallaei M, Einollahi B, Mowla SJ
The Prostate, 79:88–95, doi: 10.1002/pros.23714, 2018
The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling
Berning P, Schaefer C, Clemens D, Korsching E, Dirksen U, Potratz J
Cell Commun Signal, 16(1):21, doi: 10.1186/s12964-018-0233-2, 2018
Spatially correlated phenotyping reveals K5-positive luminal progenitor cells and p63-K5/14-positive stem cell-like cells in human breast epithelium
Boecker W, van Horn L, Stenman G, Stürken C, Schumacher U, Loening T, Liesenfeld L, Korsching E, Gläser D, Tiemann K, Buchwalow I
Lab Invest, doi: 10.1038/s41374-018-0054-3, 2018
MicroRNA expression in serum samples of sulfur mustard veterans as a diagnostic gateway to improve care
Gharbi, Sedigheh; Khateri, Shahriar; Soroush, Mohammad Reza; Shamsara, Mehdi; Naeli, Parisa; Najafi, Ali; Korsching, Eberhard*; Mowla, Seyed Javad
PLoS One, 13(3):e0194530, 10.1371/journal.pone.0194530, 2018
Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm
Schaefer, Christiane; Mallela, Nikhil; Seggewiss, Jochen; Lechtape, Birgit; Omran, Heymut; Dirksen, Uta; Korsching, Eberhard; Potratz, Jenny
PLoS One, 13(1):e0191570, 10.1371/journal.pone.0191570, 2018
Interlaboratory variability of Ki67 staining in breast cancer
Focke, Cornelia M.; Buerger, Horst; van Diest, Paul J.; Finsterbusch, Kai; Glaeser, Doreen; Korsching, Eberhard; Decker, Thomas; German Breast Screening Pathology
Eur J Cancer, 84():219-227, 10.1016/j.ejca.2017.07.041, 2017
Site-specific gene expression patterns in oral cancer
Frohwitter, Gesche; Buerger, Horst; Korsching, Eberhard; van Diest, Paul J.; Kleinheinz, Johannes; Fillies, Thomas
HEAD & FACE MEDICINE, 13():-, 10.1186/s13005-017-0138-0, 2017
Multicolor immunofluorescence reveals that p63-and/or K5-positive progenitor cells contribute to normal breast epithelium and usual ductal hyperplasia but not to low-grade intraepithelial neoplasia of the breast
Boecker, Werner; Stenman, Goran; Schroeder, Tina; Schumacher, Udo; Loening, Thomas; Stahnke, Lisa; Loehnert, Catharina; Siering, Robert Michael; Kuper, Arthur; Samoilova, Vera; Tiemann, Markus; Korsching, Eberhard; Buchwalow, Igor
VIRCHOWS ARCHIV, 470(5):493-504, 10.1007/s00428-017-2073-7, 2017
The subclonal diversity in Ewing sarcoma exhibit also a different biology
Korsching, E.; Mallela, N.; Seggewiss, J.; Jakalski, M.; Dirksen, U.; Hotfilder, M.
VIRCHOWS ARCHIV, 469():S209-S209, , 2016
Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways
Frohwitter, Gesche; Buerger, Horst; van Diest, Paul J.; Korsching, Eberhard; Kleinheinz, Johannes; Fillies, Thomas
ONCOLOGY LETTERS, 12(1):107-113, 10.3892/ol.2016.4588, 2016
Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic disease
Potratz, Jenny; Tillmanns, Amelie; Berning, Philipp; Korsching, Eberhard; Schaefer, Christiane; Lechtape, Birgit; Schleithoff, Carolin; Unland, Rebekka; Schaefer, Karl-Ludwig; Mueller-Tidow, Carsten; Juergens, Heribert; Dirksen, Uta
MOLECULAR ONCOLOGY, 10(5):677-692, 10.1016/j.molonc.2015.12.009, 2016
The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease
Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; de Alava, Enrique; Dirksen, Uta; van der Ent, Wietske; Grohar, Patrick; Grunewald, Thomas G. P.; Helman, Lee; Houghton, Peter; Iljin, Kristiina; Korsching, Eberhard; Ladanyi, Marc; Lawlor, Elizabeth; Lessnick, Stephen; Ludwig, Joseph; Meltzer, Paul; Metzler, Markus; Mora, Jaume; Moriggl, Richard; Nakamura, Takuro; Papamarkou, Theodore; Sarikas, Branka Radic; Redini, Francoise; Richter, Guenther H. S.; Rossig, Claudia; Schadler, Keri; Schaefer, Beat W.; Scotlandi, Katia; Sheffield, Nathan C.; Shelat, Anang; Snaar-Jagalska, Ewa; Sorensen, Poul; Stegmaier, Kimberly; Stewart, Elizabeth; Sweet-Cordero, Alejandro; Szuhai, Karoly; Tirado, Oscar M.; Tirode, Franck; Toretsky, Jeffrey; Tsafou, Kalliopi; Uren, Aykut; Zinovyev, Andrei; Delattre, Olivier
ONCOTARGET, 7(8):8613-8624, , 2016
TMAinspiration: Decode Interdependencies in Multifactorial Tissue Microarray Data
Boecker, Florian; Buerger, Horst; Mallela, Nikhil V.; Korsching, Eberhard
CANCER INFORMATICS, 15():143-149, 10.4137/CIN.S39112, 2016
Tracing differences between male and female breast cancer: both diseases own a different biology
Kornegoor, Robert; van Diest, Paul J.; Buerger, Horst; Korsching, Eberhard
HISTOPATHOLOGY, 67(6):888-897, 10.1111/his.12727, 2015
Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma
Agelopoulos, Konstantin; Richter, Guenther H. S.; Schmidt, Eva; Dirksen, Uta; von Heyking, Kristina; Moser, Benjamin; Klein, Hans-Ulrich; Kontny, Udo; Dugas, Martin; Poos, Kathrin; Korsching, Eberhard; Buch, Thorsten; Weckesser, Matthias; Schulze, Isabell; Besoke, Regina; Witten, Anika; Stoll, Monika; Koehler, Gabriele; Hartmann, Wolfgang; Wardelmann, Eva; Rossig, Claudia; Baumhoer, Daniel; Juergens, Heribert; Burdach, Stefan; Berdel, Wolfgang E.; Mueller-Tidow, Carsten
CLINICAL CANCER RESEARCH, 21(21):4935-4946, 10.1158/1078-0432.CCR-14-2744, 2015
A pooled shRNA lentiviral screening model to identify EWS-FLI1 specific therapeutic targets in Ewing sarcoma
Schaefer, C.; Berning, P.; Mallela, N.; Seggewiss, J.; Schleithoff, C.; Korsching, E.; Dirksen, U.; Potratz, J.
Oncology Research and Treatment, 38():246-246, , 2015
Gene expression analyses of receptor tyrosine kinases identify ROR1 as a potential therapeutic target in metastatic Ewing sarcoma
Berning, P.; Tillmanns, A.; Korsching, E.; Lechtape, B.; Schaefer, C.; Schleithoff, C.; Schaefer, K. -L; Dirksen, U.; Potratz, J.
Oncology Research and Treatment, 38():247-247, , 2015
Receptor tyrosine kinase gene expression analyses of Ewing sarcomas identify ROR1 as a potential therapeutic target in metastatic disease
Berning, P.; Tillmanns, A.; Korsching, E.; Lechtape, B.; Schaefer, C.; Schleithoff, C.; Schaefer, L.; Dirksen, U.; Potratz, J.
EUROPEAN JOURNAL OF CANCER, 51():S690-S690, , 2015
Identification of novel EWS-FLI1 specific targets in Ewing sarcoma through pooled shRNA screens
Schaefer, C.; Berning, P.; Mallela, N.; Seggewi, J.; Schleithoff, C.; Korsching, E.; Dirksen, U.; Potratz, J.
EUROPEAN JOURNAL OF CANCER, 51():S691-S691, , 2015
New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma
Maugg, Doris; Rothenaigner, Ina; Schorpp, Kenji; Potukuchi, Harish Kumar; Korsching, Eberhard; Baumhoer, Daniel; Hadian, Kamyar; Smida, Jan; Nathrath, Michaela
PLOS ONE, 10(6):-, 10.1371/journal.pone.0129058, 2015
Genomic Heterogeneity of Osteosarcoma - Shift from Single Candidates to Functional Modules
Poos, Kathrin; Smida, Jan; Maugg, Doris; Eckstein, Gertrud; Baumhoer, Daniel; Nathrath, Michaela; Korsching, Eberhard
PLOS ONE, 10(4):-, 10.1371/journal.pone.0123082, 2015
Gene expression profiling of giant cell tumor of bone reveals downregulation of extracellular matrix components decorin and lumican associated with lung metastasis
Lieveld, M.; Bodson, E.; De Boeck, G.; Nouman, B.; Cleton-Jansen, A. M.; Korsching, E.; Benassi, M. S.; Picci, P.; Sys, G.; Poffyn, B.; Athanasou, N. A.; Hogendoorn, P. C. W.; Forsyth, R. G.
VIRCHOWS ARCHIV, 465(6):703-713, 10.1007/s00428-014-1666-7, 2014
Analysis of genomic alterations in Ewing sarcoma (German cohort) reveals cooperating mutations and novel therapy targets
Richter, G. H. S.; Agelopoulos, K.; Schmidt, E.; von Heyking, K.; Moser, B.; Klein, H. U.; Kontny, U.; Dugas, M.; Poos, K.; Korsching, E.; Buch, T.; Koehler, G.; Roessig, C.; Baumhoer, D.; Juergens, H.; Burdach, S.; Berdel, W. E.; Mueller-Tidow, C.; Dirksen, U.
EUROPEAN JOURNAL OF CANCER, 50():134-134, , 2014
Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation
Poos, Kathrin; Smida, Jan; Nathrath, Michaela; Maugg, Doris; Baumhoer, Daniel; Neumann, Anna; Korsching, Eberhard
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, ():-, 10.1093/database/bau042, 2014
Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation.
Poos, Kathrin; Smida, Jan; Nathrath, Michaela; Maugg, Doris; Baumhoer, Daniel; Neumann, Anna; Korsching, Eberhard
Database : the journal of biological databases and curation, 2014():-, 10.1093/database/bau042, 2014
Interlaboratory variability of Ki67 labeling index in breast cancer tissue microarrays
Focke, C. M.; Glaeser, D.; Finsterbusch, K.; Buerger, H.; Korsching, E.; Berghaeuser, K-H; Hinrichs, B.; Krause, U.; Lorenzen, J.; Packeisen, J.; van Diest, P. J.; Decker, T.
CANCER RESEARCH, 73():-, 10.1158/0008-5472.SABCS13-P3-05-09, 2013
How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation
Poos, Kathrin; Smida, Jan; Nathrath, Michaela; Maugg, Doris; Baumhoer, Daniel; Korsching, Eberhard
PLOS COMPUTATIONAL BIOLOGY, 9(8):-, 10.1371/journal.pcbi.1003210, 2013
Effect of Acute Stressor and Serotonin Transporter Genotype on Amygdala First Wave Transcriptome in Mice
Hohoff, Christa; Gorji, Ali; Kaiser, Sylvia; Willscher, Edith; Korsching, Eberhard; Ambree, Oliver; Arolt, Volker; Lesch, Klaus-Peter; Sachser, Norbert; Deckert, Juergen; Lewejohann, Lars
PLOS ONE, 8(3):-, 10.1371/journal.pone.0058880, 2013
Chromosome 16q loss- a genetic key to the understanding of breast carcinogenesis
Buerger, Horst; de Boer, Mirthe; van Diest, Paul J.; Korsching, Eberhard
HISTOLOGY AND HISTOPATHOLOGY, 28(3):311-320, , 2013
Analyzing the basic principles of tissue microarray data measuring the cooperative phenomena of marker proteins in invasive breast cancer
Buerger H.; Boecker F.; Packeisen J.; Agelopoulos K.; Poos K.; Nadler W.; Korsching E.
Open Access Bioinformatics, 5(1):1-21, 10.2147/OAB.S36565, 2013
Is there 'progression through grade' in ductal invasive breast cancer?
Schymik, Barbara; Buerger, Horst; Kraemer, Annika; Voss, Ulli; van der Groep, Petra; Meinerz, Wolfgang; van Diest, Paul J.; Korsching, Eberhard
BREAST CANCER RESEARCH AND TREATMENT, 135(3):693-703, 10.1007/s10549-012-2195-1, 2012
Systematic analysis of in vitro chemosensitivity and mib-1 expression in molecular breast cancer subtypes
Liedtke, Cornelia; Packeisen, Jens; Hess, Kenneth R.; Vogt, Ulf; Kiesel, Ludwig; Kersting, Christian; Korsching, Eberhardt; Brandt, Burkhard; Buerger, Horst
EUROPEAN JOURNAL OF CANCER, 48(13):2066-2074, 10.1016/j.ejca.2011.08.006, 2012
Origin and differentiation of breast nipple syringoma
Boecker, Werner; Junkers, Tina; Reusch, Michael; Buerger, Horst; Korsching, Eberhard; Metze, Dieter; Decker, Thomas; Loening, Thomas; Lange, Alina; Samoilova, Vera; Buchwalow, Igor
SCIENTIFIC REPORTS, 2():-, 10.1038/srep00226, 2012
Site-specific chromatin immunoprecipitation: a selective method to individually analyze neighboring transcription factor binding sites in vivo.
Schuch, Ronaldo; Agelopoulos, Konstantin; Neumann, Anna; Brandt, Burkhard; Burger, Horst; Korsching, Eberhard
BMC research notes, 5():109-109, 10.1186/1756-0500-5-109, 2012
Characterization of Hematopoietic Progenitor Kinase 1 (HPK1) in Multiple Myeloma: a Player in Pathogenesis?
Bisping, Guido; Gustavus, Dirk; Kiefer, Friedemann; Korsching, Eberhard; Kienast, Joachim; Berdel, Wolfgang E.
BLOOD, 118(21):1692-1692, , 2011
"Minimal Invasive Biopsy Results of ""Uncertain Malignant Potential"" in Digital Mammography Screening: High Prevalence but also High Predictive Value for Malignancy"
Weigel, S.; Decker, T.; Korsching, E.; Biesheuvel, C.; Woestmann, A.; Boecker, W.; Hungermann, D.; Roterberg, K.; Tio, J.; Heindel, W.
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 183(8):743-748, 10.1055/s-0031-1273330, 2011
Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer
Hungermann, Daniela; Schmidt, Hartmut; Natrajan, Rachel; Tidow, Nicola; Poos, Kathrin; Reis-Filho, Jorge S.; Brandt, Burkhard; Buerger, Horst; Korsching, Eberhard
JOURNAL OF PATHOLOGY, 224(4):517-528, 10.1002/path.2938, 2011
Keratin 5/14+Progenitor Cell Concept of Breast Epithelium: Revisited
Boecker, W.; Hallas, C.; Korsching, E.; Stahnke, L.; Decker, T.; Tio, J.; Weigel, S.; Buchwalow, I.; Loening, T.
Cancer Research, 70(Suppl. 24):P6-01-08, 10.1158/0008-5472.SABCS10-P6-01-08, 2010
New Concept of the Histogenesis of Salivary Gland-Like Tumors of the Breast as K5/14-Positive Progenitor Lesions
Boecker, W.; Bankfalvi, A.; Hallas, C.; Buchwalow, I.; Herbst, H.; Loening, T.
CANCER RESEARCH, 70():-, 10.1158/0008-5472.SABCS10-P6-01-07, 2010
Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4
Knowles, Helen J.; Cleton-Jansen, Anne-Marie; Korsching, Eberhard; Athanasou, Nicholas A.
FASEB JOURNAL, 24(12):4648-4659, 10.1096/fj.10-162230, 2010
Genomic Alterations and Allelic Imbalances Are Strong Prognostic Predictors in Osteosarcoma
Smida, Jan; Baumhoer, Daniel; Rosemann, Michael; Walch, Axel; Bielack, Stefan; Poremba, Christopher; Remberger, Klaus; Korsching, Eberhard; Scheurlen, Wolfram; Dierkes, Christian; Burdach, Stefan; Jundt, Gernot; Atkinson, Michael J.; Nathrath, Michaela
CLINICAL CANCER RESEARCH, 16(16):4256-4267, 10.1158/1078-0432.CCR-10-0284, 2010
Calcifications in Digital Mammographic Screening: Improvement of Early Detection of Invasive Breast Cancers?
Weigel, Stefanie; Decker, Thomas; Korsching, Eberhard; Hungermann, Daniela; Boecker, Werner; Heindel, Walter
RADIOLOGY, 255(3):738-745, 10.1148/radiol.10091173, 2010, 26
OSTEOCLAST-MEDIATED BONE RESORPTION: REGULATION BY HYPOXIA-INDUCIBLE FACTOR (HIF) AND ANGIOPOIETIN-LIKE 4 (ANGPTL4)
Knowles, Helen; Cleton-Jansen, Anne-Marie; Korsching, Eberhard; Athanasou, Nick
RHEUMATOLOGY, 49():I28-I28, 10.1093/rheumatology/keq710, 2010
Selective regain of egfr gene copies in CD44(+)/CD24(-/low) breast cancer cellular model MDA-MB-468
Agelopoulos, Konstantin; Greve, Burkhard; Schmidt, Hartmut; Pospisil, Heike; Kurtz, Stefan; Bartkowiak, Kai; Andreas, Antje; Wieczorek, Marek; Korsching, Eberhard; Buerger, Horst; Brandt, Burkhard
BMC CANCER, 10():-, 10.1186/1471-2407-10-78, 2010
Hypoxia-Inducible Factor (HIF) regulates Osteoclast-Mediated Bone Resorption via Angiopoietin-like 4 (ANGPTL4)
Knowles, Helen; Cleton-Jansen, Anne-Marie; Korsching, Eberhard; Athanasou, Nick
BONE, 46():S63-S63, 10.1016/j.bone.2010.01.151, 2010
Expression of the Endothelin Axis in Noninvasive and Superficially Invasive Bladder Cancer: Relation to Clinicopathologic and Molecular Prognostic Parameters
Eltze, Elke; Wild, Peter J.; Wuelfing, Christian; Zwarthoff, Ellen C.; Burger, Maximilian; Stoehr, Robert; Korsching, Eberhard; Hartmann, Arndt
EUROPEAN UROLOGY, 56(5):837-845, 10.1016/j.eururo.2008.10.003, 2009
Margin width and size as predictors of residual tumour in breast conserving therapy of ductal carcinoma in situ
Decker, T.; Ruhnke, M.; Obenaus, R.; Kettritz, U.; Roterberg, K.; Tio, J.; Hungermann, D.; Korsching, E.; Boecker, W.
VIRCHOWS ARCHIV, 455():40-40, , 2009
Diagnostics of microcalcifications from minimally invasive biopsies in mammography screening
Hungermann, D.; Weigel, S.; Korsching, E.; Heindel, W.; Boecker, W.; Decker, T.
PATHOLOGE, 30(1):31-35, 10.1007/s00292-008-1100-5, 2009
[Different coexisting genotypes in the breast cancer cell line MDA-MB-468].
Agelopoulos, K; Schmidt, H; Korsching, E; Buerger, H; Brandt, B
Der Pathologe, 29 Suppl 2():333-7, 10.1007/s00292-008-1021-3, 2008
Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+breast cancer and indicates poor clinical outcome in stage I and II disease
Helms, M. W.; Kemming, D.; Pospisil, H.; Vogt, U.; Buerger, H.; Korsching, E.; Liedtke, C.; Schlotter, C. M.; Wang, A.; Chan, S. Y.; Brandt, B. H.
BRITISH JOURNAL OF CANCER, 99(5):774-780, 10.1038/sj.bjc.6604556, 2008
Biological importance of a polymorphic CA sequence within intron 1 of the epidermal growth factor receptor gene (EGFR) in high grade central osteosarcomas
Kersting, Christian; Agelopoulos, Konstantin; Schmidt, Hartmut; Korsching, Eberhard; August, Christian; Gosheger, Georg; Dirksen, Uta; Juergens, Heribert; Winkelmann, Wilfried; Brandt, Burkhard; Bielack, Stefan; Buerger, Horst; Gebert, Carsten
GENES CHROMOSOMES & CANCER, 47(8):657-664, 10.1002/gcc.20571, 2008
Basal carcinoma of the breast revisited: an old entity with new interpretations
Korsching, E.; Jeffrey, S. S.; Meinerz, W.; Decker, T.; Boecker, W.; Buerger, H.
JOURNAL OF CLINICAL PATHOLOGY, 61(5):553-560, 10.1136/jcp.2008.055475, 2008
Identifying cellular mechanisms of organ-specific metastasis of Ewing sarcoma
Knizia, H.; Unland, R.; Hotfilder, M.; Korsching, E.; Dirksen, U.; Juergens, H.; Vormoor, J.
KLINISCHE PADIATRIE, 220(3):203-203, , 2008
Differential expression of ER and Ki67 in normal breast tissue and proliferating breast disease: further support of the progenitor cell concept?
Boecker, W.; Loechnert, C.; Korsching, E.
EJC SUPPLEMENTS, 5(3):4-5, 10.1016/S1359-6349(07)71703-2, 2007
Expression and prognostic relevance of endothelin-B receptor in vulvar cancer
Eltze, Elke; Bertolin, Matteo; Korsching, Eberhard; Wuelfing, Pia; Maggino, Tiziano; Lelle, Ralph
ONCOLOGY REPORTS, 18(2):305-311, , 2007
Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene
Spinola, Monica; Leoni, Vera P.; Galvan, Antonella; Korsching, Eberhard; Conti, Barbara; Pastorino, Ugo; Ravagnani, Fernando; Columbano, Amedeo; Skaug, Vidar; Haugen, Aage; Dragani, Tommaso A.
CANCER LETTERS, 251(2):311-316, 10.1016/j.canlet.2006.11.029, 2007
Salivary duct carcinomas comprise phenotypically and genotypically diverse high-grade neoplasms
Hungermann, D.; Korsching, E.; Buerger, H.; Roeser, K.; Loening, T.; Herbst, H.
HISTOPATHOLOGY, 50(7):956-958, 10.1111/j.1365-2559.2007.02701.x, 2007
Egfr amplification specific gene expression in phyllodes tumours of the breast
Agelopoulos, Konstantin; Kersting, Christian; Korsching, Eberhard; Schmidt, Hartmut; Kuijper, Arno; August, Christian; Wuelfing, Pia; Tio, Joke; Boecker, Werner; van Diest, Paul J.; Brandt, Burkhard; Buerger, Horst
CELLULAR ONCOLOGY, 29(6):443-451, , 2007
Mutation analyses of candidate genes detected by CGH on chromosome 16q in invasive breast carcinoma
Schmidt, H.; Hungermann, D.; Agelopoulos, K.; Korsching, E.; Brandt, B.; Boecker, W.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):262-262, , 2007
Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR validated by tissue micro array
Schmidt, H.; Semjonow, A.; Csiszar, K.; Korsching, E.; Brandt, B.; Eltze, E.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):278-278, , 2007
Increased EGFR expression is associated with reduced progression-free and overall survival rates
Neumann, J.; Herrmann, E.; Korsching, E.; Buerger, H.; Bierer, S.; Bocker, W.; Wulfing, C.; Eltze, E.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):310-311, , 2007
Expression of the endothelin-B receptor a prognostic factor in renal cancer
Eltze, E.; Herrmann, E.; Korsching, E.; Neumann, J.; Bierer, S.; Balnowair, H.; Bocker, W.; Wulfing, C.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):312-312, , 2007
Genetic factors for invasiveness in osteosarcomas
Agelopoulos, K.; Neumann, A.; Schmidt, H.; Korsching, E.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):336-337, , 2007
Gene expression analysis of 36 Ewing sarcomas by microarray techniques - evidence for 3 subgroups and comparison with existing gene profiles
Korsching, E.; Schmidt, H.; Koehler, G.; Boecker, W.; Juergens, H.; Buerger, H.; Dirksen, U.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):337-337, , 2007
Analysing genetic processes in EGFR regulation refining the prediction of tumour response to cancer treatments in high grade osteosarcomas
Korsching, E.; Agelopoulos, K.; Schmidt, H.; Gebert, C.; Winkelmann, W.; Gosheger, G.; Buerger, H.; Kersting, C.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):337-337, , 2007
Analysis of the eigenvalues of microarray data concerning the objective to detect regulatory networks in a set of cancer markers
Korsching, E.; Buerger, H.; Schmidt, H.; Agelopoulos, K.; Boecker, W.; Nadler, W.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):347-347, , 2007
Screening for egfr mutations of exon 18, 19 and 21 in non-small cell lung cancers - a report from molecular routine diagnostics
Schmidt, H.; Agelopoulos, K.; Korsching, E.; Eltze, E.; Brandt, B.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):387-387, , 2007
Detection and charakterization of amplified chromosomal regions in human tumors by single nucleotide polymorphism (SNP) analysis
Korsching, E.; Agelopoulos, K.; Schmidt, H.; Kersting, C.; Boecker, W.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):396-397, , 2007
Activation of the EGFR pathway is independent of the EGFR expression level
Agelopoulos, K.; Schmidt, M.; Schmidt, H.; Korsching, E.; Buerger, H.; Brandt, B.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):399-399, , 2007
Identification of egfr specific transcription factor binding sites via chromatin immunoprecipitatioin and sequence specific restriction
Agelopoulos, K.; Schuch, R.; Schmidt, H.; Korsching, E.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):400-400, , 2007
Cancer cells andregulation - Software package on the basis of R and S-Plus to integrate microarray data from single nucleotide polymorphism, (SNP) and gene expression platforms
Korsching, E.; Nadler, W.; Schmidt, H.; Agelopoulos, K.; Boecker, W.; Buerger, H.
PATHOLOGY RESEARCH AND PRACTICE, 203(5):415-415, , 2007
[Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR].
Schmidt, H; Semjonow, A; Csiszar, K; Korsching, E; Brandt, B; Eltze, E
Verhandlungen der Deutschen Gesellschaft fur Pathologie, 91():302-7, , 2007
Chromosomal losses of regions on 5q and lack of high-level amplifications at 8q24 are associated with favorable prognosis for ovarian serous carcinoma
Staebler, Annette; Karberg, Bianca; Behm, Juliane; Kuhlmann, Petra; Neubert, Ulrike; Schmidt, Hartmut; Korsching, Eberhard; Buerger, Horst; Lelle, Ralph; Kiesel, Ludwig; Boecker, Werner; Shih, Le-Ming; Buchweitz, Olaf
GENES CHROMOSOMES & CANCER, 45(10):905-917, 10.1002/gcc.20356, 2006
Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression
Seitz, S; Korsching, E; Weimer, J; Jacobsen, A; Arnold, N; Meindl, A; Arnold, W; Gustavus, D; Klebig, C; Petersen, I; Scherneck, S
GENES CHROMOSOMES & CANCER, 45(6):612-627, 10.1002/gcc.20325, 2006
Whole genome expression analysis for biologic rational pathway modeling - Application in cancer prognosis and therapy prediction
Kemming, D.; Vogt, U.; Tidow, N.; Schlotter, C. M.; Buerger, H.; Helms, M. W.; Korsching, E.; Granetzny, A.; Boseila, A.; Hillejan, L.; Marra, A.; Ergoenenc, Y.; Adiguezel, H.; Brandt, B.
MOLECULAR DIAGNOSIS & THERAPY, 10(5):271-280, , 2006
Improvements in the analysis strategy make single nucleotide polymorphism analysis a powerful tool in the detection and characterization of amplified chromosomal regions in human tumors
Korsching, E; Agelopolous, K; Schmidt, H; Buchroth, I; Gosheger, G; Wulfing, P; Boecker, W; Brandt, B; Buerger, H
PATHOBIOLOGY, 73(1):18-25, 10.1159/000093088, 2006
[Salivary duct carcinomas comprise phenotypically and genotypically diverse high grade neoplasms].
Hungermann, Daniela; Korsching, Eberhard; Burger, Horst; Roser, Kerstin; Loning, Thomas; Herbst, Hermann
Verhandlungen der Deutschen Gesellschaft fur Pathologie, 90():168-76, , 2006
Expression of the endothelin axis in vulvar cancer - An immunohistochemical study and relationship to long-term follow up
Eltze, E.; Bertolin, M.; Korsching, E.; Wuelfing, P.; Maggino, T.; Lelie, R.
Anticancer Research, 25(6D):4789-4789, , 2005
Profile of differentially expressed genes after transfer of chromosome 17 into the breast cancer cell line CAL51
Klebig, C; Seitz, S; Korsching, E; Kristiansen, G; Gustavus, D; Scherneck, S; Petersen, I
GENES CHROMOSOMES & CANCER, 44(3):233-246, 10.1002/gcc.20240, 2005
Re: Korsching et al. The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol 2005; 206: 451-457 - Reply
Korsching, E; van Diest, PJ; Buerger, H
JOURNAL OF PATHOLOGY, 207(3):370-371, 10.1002/path.1834, 2005
Influence of different mechanisms of chromosomal 16q-loss in invasive breast cancer on differential gene expression
Buerger, H; Korsching, E; Kemming, D; Cleton-Jansen, AM; Boecker, W; Brandt, B
JOURNAL OF PATHOLOGY, 207():5-5, , 2005
Epidermal Growth Factor Receptor (EGFR) expression and mutation patterns in high malignant central osteosarcomas
Kersting, C; Korsching, E; Schmidt, H; Bielack, S; Gosheger, G; Gebert, C; van Diest, PJ; Brandt, B; Buerger, H
JOURNAL OF PATHOLOGY, 207():53-53, , 2005
The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential?
Korsching, E; Packeisen, J; Liedtke, C; Hungermann, D; Wulfing, P; van Diest, PJ; Brandt, B; Boecker, W; Buerger, H
JOURNAL OF PATHOLOGY, 206(4):451-457, 10.1002/path.1797, 2005
Identification of clinically relevant gene sets and pathways using functional models of breast tumor suppression
Seitz, S; Korsching, E; Weimer, J; Jacobsen, A; Arnold, N; Meindl, A; Arnold, W; Gustavus, D; Klebig, C; Petersen, I; Scherneck, S
BREAST CANCER RESEARCH, 7():S39-S39, 10.1186/bcr1143, 2005
Assembling whole genome expression analysis data from snapshots of cancer cellconditions to decipher stages of differentiation
Brandt, B; Kemming, D; Tidow, N; Burger, H; Voss, R; Korsching, E
CELLULAR ONCOLOGY, 27(2):95-96, , 2005
Bootstrapping approach reveals inherent regulatory pattern in 550 invasive breast cancer cases: CK5/6/CK 14 and CK8/18/CK 19 builds an antagonistic set
Korsching, E.; Packeisen, J.; Voss, R.; Boecker, W.; Buerger, H.
Pathology Research and Practice, 201(3):162-163, , 2005
Origin of vimentin expression in invasive breast cancer: Epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential?
Burger, H.; Korsching, E.; Packeisen, J.; Hungermann, D.; Liedtke, C.; Decker, T.; Boecker, W.
Pathology Research and Practice, 201(3):171-171, , 2005
Influence of different mechanisms of chromosomal 16q-loss in invasive breast cancer on differential gene expression
Buerger, H.; Korsching, E.; Cleton-Jansen, A. M.; Kemming, D.; Schmidt, H.; Tidow, N.; Brandt, B.; Boecker, W.
Pathology Research and Practice, 201(3):216-216, , 2005
Multiconditional gene expression analysis in microarray experiments supports the characterization of tumor progression pathways on a molecular level
Korsching, E.; Buerger, H.; Brandt, B.; Boecker, W.; Voss, R.
Pathology Research and Practice, 201(3):223-223, , 2005
Biomathematical cluster analyses of immunohistochemical results on a tissue microarray of 57 malignant salivary gland tumors: The importance of a new method in stem cell concept of tumorigenesis
August, C. H.; Alberty, J.; Packeisen, J.; Tappe, H.; Buerger, H.; Hungermann, D.; Boecker, W.; Korsching, E.
Pathology Research and Practice, 201(3):284-284, , 2005
[Bootstrapping algorithm approach reveals inherent regulatory pattern in 550 invasive breast cancer cases: CK5/6/CK14 and CK8/18/CK19 builds an antagonistic set].
Korsching, E; Packeisen, J; Bocker, W; Burger, H
Verhandlungen der Deutschen Gesellschaft fur Pathologie, 89():207-10, , 2005
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3
Schaefer, KL; Brachwitz, K; Wai, DH; Braun, Y; Diallo, R; Korsching, E; Eisenacher, M; Voss, R; van Valen, F; Baer, C; Selle, B; Spahn, L; Liao, SK; Lee, KAW; Hogendoorn, PCW; Reifenberger, G; Gabbert, HE; Poremba, C
CANCER RESEARCH, 64(10):3395-3405, 10.1158/0008-5472.CAN-03-0809, 2004
Deciphering a subgroup of breast carcinomas with putative progression of grade during carcinogenesis revealed by Comparative Genomic Hybridisation (CGH) and immunohistochemistry
Korsching, E; Packeisen, J; Helms, MW; Kersting, C; Voss, R; van Diest, PJ; Brandt, B; van der Wall, E; Boecker, W; Burger, H
BRITISH JOURNAL OF CANCER, 90(7):1422-1428, 10.1038/sj.bjc.6601658, 2004
c-erbB2 regulates cytokeratin expression patterns of invasive breast cancer cells
Buerger, H.; Kemming, D.; Korsching, E.; Helms, M.; Agelopoulos, K.; Brandt, B.; Boecker, W.
Pathology Research and Practice, 200(4):304-304, , 2004
Cytokeratin expression patterns and progenitor cells of invasive breast cancer
Packeisen, J.; Korsching, E.; Liedtke, C.; Kemming, D.; Brandt, B.; Boecker, W.; Buerger, H.
Pathology Research and Practice, 200(4):350-350, 10.1016/S0344-0338(04)80753-2, 2004
Molecular cytogenetic investigations of synchronous bilateral breast cancer
Agelopoulos, K; Tidow, N; Korsching, E; Voss, R; Hinrichs, B; Brandt, B; Boecker, W; Buerger, H
JOURNAL OF CLINICAL PATHOLOGY, 56(9):660-665, 10.1136/jcp.56.9.660, 2003
Demystified ... Tissue microarray technology
Packeisen, J; Korsching, E; Herbst, H; Boecker, W; Buerger, H
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 56(4):198-204, , 2003
The value of tissue micro arrays (TMA's) in experimental pathology.
Packeisen, J.; Korsching, E.; van Diest, P. J.; Brandt, B.; Krech, R.; Boecker, W.; Buerger, H.
Pathology Research and Practice, 199(4):246-246, , 2003
Influence of physiological breast differentiation and cytokeratin expression patterns on breast carcinogenesis.
Packeisen, J.; Korsching, E.; Kersting, C.; van Diest, P. J.; Brandt, B.; Boecker, W.; Buerger, H.
Pathology Research and Practice, 199(4):276-277, , 2003
Molecularcytogenetic investigations of synchronous bilateral breast cancer.
Agelopoulos, K; Korsching, E; Hinrichs, B; Boecker, W; Brandt, B; Buerger, H
BREAST CANCER RESEARCH AND TREATMENT, 76():S102-S102, , 2002
Cytogenetic alterations and cytokeratin expression patterns in breast cancer - integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis.
Buerger, H; Korsching, E; Packeisen, J; Van Diest, PJ; Isola, J; Brandt, B; Boecker, W
BREAST CANCER RESEARCH AND TREATMENT, 76():S144-S144, , 2002
Cytogenetic alterations and cytokeratin expression patterns in breast cancer: Integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis
Korsching, E; Packeisen, J; Agelopoulos, K; Eisenacher, M; Voss, R; Isola, J; van Diest, PJ; Brandt, B; Boecker, W; Buerger, H
LABORATORY INVESTIGATION, 82(11):1525-1533, 10.1097/01.LAB.0000038508.86221.B3, 2002
Tissue micro arrays (TMA's) as a now tool in experimental pathology
Packeisen, J; Buerger, H; Korsching, E; Eisenacher, M; van Diest, PJ; Brandt, B; Krech, R; Boecker, W
JOURNAL OF PATHOLOGY, 198():2A-2A, , 2002
Cytogenetic and protein expression patterns - influence of physiological breast differentiation on breast carcinogenesis
Buerger, H; Packeisen, J; Korsching, E; Kersting, C; van Diest, PJ; Brandt, B; Boecker, W
JOURNAL OF PATHOLOGY, 198():3A-3A, , 2002
Characterization of the malignant melanoma of soft-parts cell line GG-62 by expression analysis using DNA microarrays
Schaefer, KL; Wai, DH; Poremba, C; Korsching, E; van Valen, F; Ozaki, T; Boecker, W; Dockhorn-Dworniczak, B
VIRCHOWS ARCHIV, 440(5):476-484, 10.1007/s00428-001-0558-9, 2002
Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays
Wai, Daniel H.; Schaefer, Karl-Ludwig; Schramm, Alexander; Korsching, Eberhard; van Valen, Frans; Ozaki, Toshifumi; Boecker, Werner; Schweigerer, Lothar; Dockhorn-Dworniczak, Barbara; Poremba, Christopher
International Journal of Oncology, 20(3):441-451, , 2002
Expression analysis of pediatric solid tumor cell lines using oligonucleotide microarrays
Wai, DH; Schaefer, KL; Schramm, A; Korsching, E; Van Valen, F; Ozaki, T; Boecker, W; Schweigerer, L; Dockhorn-Dworniczak, B; Poremba, C
INTERNATIONAL JOURNAL OF ONCOLOGY, 20(3):441-451, , 2002
Clinical interoperability: Taking telepathology to the next level
Ganslandt, T.; Korsching, E.; Prokosch, H. U.; Herbst, H.; Boecker, W.; Senninger, N.; Spiegel, H. U.
Virchows Archiv, 439(3):253-253, , 2001
No need for standards? Telepathology in the view of Nikon, Zeiss, Olympus and Leica
Korsching, E.; Ganslandt, T.; Prokosch, H. U.; Herbst, H.; Boecker, W.; Senninger, N.; Spiegel, H. U.
Virchows Archiv, 439(3):254-254, , 2001
Telepathology network: conceptual groundwork and evaluation.
Ganslandt, T; Korsching, E; Muller, M L; Herbst, H; Spiegel, H U; Prokosch, H U; Senninger, N
Studies in health technology and informatics, 77():1122-6, , 2000
Generation of type VIII collagen-specific antibodies
Korsching, E; Rauterberg, J
JOURNAL OF IMMUNOLOGICAL METHODS, 188(1):51-62, 10.1016/0022-1759(95)00201-4, 1995
Type VIII collagen is an integral component of the matrix of the vessel wall
Korsching, E.; Rauterberg, J.
European Journal of Cell Biology, 63(SUPPL. 40):6-6, , 1994
THE PRIMARY STRUCTURE OF A TRIPLE-HELICAL DOMAIN OF COLLAGEN TYPE-VIII FROM BOVINE DESCEMETS-MEMBRANE
MANN, K; JANDER, R; KORSCHING, E; KUHN, K; RAUTERBERG, J
FEBS LETTERS, 273(1-2):168-172, 10.1016/0014-5793(90)81076-Z, 1990
CHARACTERISTICS AND INVIVO OCCURRENCE OF TYPE-VIII COLLAGEN
JANDER, R; KORSCHING, E; RAUTERBERG, J
EUROPEAN JOURNAL OF BIOCHEMISTRY, 189(3):601-607, 10.1111/j.1432-1033.1990.tb15528.x, 1990
TYPE-VIII COLLAGEN - STRUCTURAL STUDIES ON A PEPSIN FRAGMENT AND OCCURRENCE IN DIFFERENT TISSUES
JANDER, R; MANN, K; TROYER, D; KORSCHING, E; RAUTERBERG, J
BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 370(9):914-914, , 1989